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A recent programme examining 4006 proteins from serum, CSF and brain tissue 114 , identified a signature of proteins more strongly associated with PD (with AUC ranging from 0.66 for serum, to 0.75 for brain tissue), including proteins from cytokine receptor interaction and complement pathways

FR carries the potential capability of binding to a molecule of small and comparatively innocuous nature, i.e., folic acid that forms chemical conjugation with other molecules and is known to significantly infiltrate the developed solid tumors

The best candidates can then be combined with gene HI fusions that encode pathogenic epitopes of interest

Etheridge ML, Campbell SA, Erdman AG, Haynes CL, Wolf SM, McCullough J (2013) The big picture on nanomedicine: the state of investigational and approved nanomedicine products

Drug-induced miRNAs including miR-21-3p have been shown to control MAT2A and MAT2B stability in HepG2 cells